The Vet is too expensive! I live on a farm that borders a forest, so coyotes/deer etc.. no avoiding ticks. Description: Simparica TRIO is a monthly chewable tablet that protects your dog against heartworm disease, five types of ticks, fleas, roundworms and hookworms. Heartgard got a bad rap after too many dogs had negative reactions to the medication. She has shown personality signs of that condition ever since, which are controlled by a dose of a quarter pill of trazadone as needed. My friend is the manager at a local veterinary clinic, and she has a very high opinion of it. 3,4,7-9 Most notably, a series of randomized . Either Sentinel or Interceptor are generally considered safe for Collies and can be used to treat demodectic mange. If the veterinary staff cant see they are prescribing the wrong combination of medications, maybe you can point it out to them.. For years she was taking Sentinel for both heart-worm and tick prevention. I will not give anything oral to my dog, since our first collie was probably killed by heartworm preventative. MDR1 FAQs. You can even scatter some on your dogs bed. The topical medicines seem to work best with her, but dont do much to keep the tics at bay. It should be given with food (as should any oral medication, really) to avoid a possible upset stomach. We use interceptor for heartworms and was using frontline until she recently started having negative reactions to it. Simparica Trio can be described as a broad-spectrum parasite preventative that offers protection and treatment to dogs. Im happy to hear it and so glad it helped! However, it will not affect heartworms at all, since they do not infest the gastrointestinal tract. Doses used for heartworm prevention are safe to use in these breeds of dogs. 2022 Collie Chatter. Prevents: Heartworm, Fleas, Intestinal worms (except tapeworm) Comes as: a meaty chew given once every month (afoxolaner & milbemycin) Simparica Trio is proven to kill 5 species of ticks. Nexgard and Simparica. Congratulations on the new kitten. Another safe heartworm medication is the daily dimmitrol. . Happy to help! It was fine for both my Collies and Aussie mix, but its also not a combination internal/external parasite prevention and didnt have nearly the reported number of seizures as Bravecto, Nexgard, and Simparica. Does your veterinarian give other reasons for prescribing Credelio vs. similar brands? Emma. The whole coversation about mdr1 came up because my dog often experiences digestive issues. I tried to review a variety of the most well-known parasite protection products out there, but if I left out any you are curious about, leave a comment below! We do eat it! Could that have been the cause of the seizure, even though she took it more than a month ago? Based on my findings, Im not convinced of its superior safety. I would say you are right to be concerned, and Ill give some info why. Thank you. Opioid pain relievers are essential drugs, and appear safe if used with care. Ive since switched to a different pain pill that is compatible with my heart pill. I need to pivot, and looking at Frontline there are two new Frontline products to combat the flea resistance. However, it did make my Collies too itchy. This is a new extensively tested product now available in Australia that provides optimal protection for your dog. . This is typically due to a specific genetic mutation (MDR1) that makes them less able to tolerate high doses of ivermectin. Id like to have a Smooth Collie in the future. Material name: Simparica Trio Version #: 01 Issue date: 07-01-2019 SDS US. Thanks for reply. Selamectin is their shared main ingredient. I found a paper on the web written with credits to several vets. However, Ive had the best results with a medicated ear mite treatment prescribed by my veterinarian. Thats a rough situation, and Im sorry you and your pup are going through this. Bear in mind that my opinion is by no means professional, but personally Id go with your first vets prescription. According to the Vet UK website, Matching game, word search puzzle, and hangman also available. (If you order online, keep in mind that the company will first have to contact your veterinarian for a prescription to be issued, which may slightly delay the shipping time.). Its worth making a phone call to see what they would recommend for your pup. My other vet never brought this up when discussing my MAS. So, what do you think of Parastar Plus? Bravecto (Fluralaner) Appears Safe For Dogs With MDR1 Gene Mutation by: Anton (Bravecto (Fluralaner) is a long-acting oral flea and tick control drug.) (One such knockoff, Pet Armor Plus, is even available at Walmart.). Simparica TRIO Chews for Dogs 44-88 lbs (20.1-40 kg) - Green 6 Chews (11/2024 Expiry) Was: $115.99. User warnings Wash hands after handling the product. (357 reviews) Simparica. 1x 20mg tablet for 11.1 to 22 pounds. Now: $92.79. Product Description. This monthly chewable is recommended for 8 weeks and older dogs, weighing 2.8 lbs or more. Somewhere I read that its good for 4 kinds. Thank you, and hello to Nola and Otis! I have a 8 yr old MAS/Aussie who is MDR1 +/+ and I have her on Trifexis and have had no issues to date. Are you also on Instagram, by chance? Dr. Judy Morgan described the case of a Beagle brought to her that was suffering from seizures, which were likely the result of or worsened by being wrongly prescribed Nexgard in combination with another medication. So far, noone has the answer to this seemingly-simple question as to what ticks their product actually acts against. I was leaning towards, but have not tried, the combination of Interceptor tablets (heartworm) + Credilio (flea and tick) tablets. Wondercide sounds like an excellent place to start as far as flea and tick prevention, and I hope it will be effective against mosquitoes, too. I have a new Collie-mix with bi-coloured coat. THREE OF THE 8 FEMALES WENT INTO ESTRUS. It is approved for use on puppies at least 3 pounds in weight and 7 weeks of age, cats, and even ferrets. LIST OF DRUGS THAT CAUSE SENSITIVITY TO DOGS WITH MDR1 MUTATION. Simparica Trio is the first and only product that combines sarolaner, moxidectin, and pyrantel in one simple-to-give chewable-for protection against heartworm disease, ticks & fleas, roundworms & hookworms.. One chewable tablet provides month-long protection for all dogs over 8 weeks old and weighing 2.8 pounds or more. I liked your post very informative I have a border collie that I think has the mdr1 gene we are going to have her tested it seems whatever we give her she has a side effect I would like to know if you have any information for pain drugs or natural medicine she has some arthritis and has sprained her leg. The amped-up version, Interceptor Plus, also contains praziquantel, which is used to treat tapeworms. , I use Advecta 3 because it prevents and kills I have been in the dog Bussiness for over 26 years and used to use frontline bit past few years switched because frontline doesnt prevent .I never had a problem with advecta 3 and hope its safe, As this is a Collie blog and I assume the majority of people who read this post have a Collie, Im just hesitant to recommend it since many Collies have issues with sensitive skin even if theyre clear of MDR1. Simparica TRIOse administra va oral una vez al mes, a una dosis de 1.2 mg de sarolaner/kg de peso corporal; . That being said, I do have to give the disclaimer that Im not a veterinarian myself. Thank you for such a great article! Dogs with the MDR1 genetic mutation can become very ill or die if given certain medications. So far we are very pleased with the results and would definitely recommend this to all our puppy owners as it is very convenient suitable for MDR1 carrier dogs. Many Rough Collie owners swear by them, and one owner mentioned that she lives in the woods and the Seresto collars kept the ticks off her Roughs. Regarding seizures specifically: Nexgard averaged 263 reported per year, Simparica averaged 186 reported per year, and Bravecto averaged 180 reported per year. I plan to switch him over to Trifexis also. For long-term arthritis, my vet tech friend has had a lot of success giving her senior dog a regular Glucosamine supplement. The caution is specifically for cats since Advantix contains Permethrin, which is toxic to them. Hi there , thank you for putting this information up! Moxidectin, the heartworm-fighting portion of Advantage, is considered safe if the proper dosage is given monthly, but it did not test as well as either selamectin or milbemycin oxime in clinical trials, though it ranks above Ivermectin. This article from Your Dog Advisor gives more natural prevention options and even tells you how to mix your own parasite preventives using essential oils and water. I have to state the disclaimer that Im not a vet just someone who took a Research and Publishing class in college. It was both well written, and concise. Hi Vicki, It was winter. For me, every medicine has its side effects, and it really comes down to weighing the risk of side effects against the risks posed by parasites. I have a cat myself, so I appreciate the information. We gave her the first dose in late February and there were no adverse side effects for Sugar. Select in Checkout The other thing is he is small for a male (30 lbs) and the Sentinel dose is for 26-50 lbs, which I think is part of the problem. Most veterinarians in my area are still prescribing Bravecto, simply because they arent yet comfortable enough with Credelio. thanks for your research. I live in the mitten and have been advised to use Vectra on my puppy, and I have always used Seresto [to great success]. So heres the culmination of my research: information gathered from laboratory case studies, veterinarians, and Collie owners, breeders, and exhibitors. But it doesnt hurt mammals. Happy to help! Took that collar right off her. a thorough study conducted on MDR1-affected dogs, this study conducted on twenty MDR1-affected Collies, the Washington State University of Veterinary Medicine, safe for use with anthelmintics like heartworm meds, Some swear by food grade DE (diatomaceous earth) as a natural dewormer. The neurological problems tied to Simparica scare the shit out . Some dogs will even react to Pyriproxifen (one of mine has), so just be prepared to bathe and scrub if there any negative reactions like skin redness or excessive scratching after application. 50% Off First Repeat Delivery. - It is easy to administer, with no need for pre-treatment or fasting. Second, Id like to ask a question if you dont mind. However, its technically safe so long as it isnt applied past the shoulder blades where your Collie could reach it. Sarolaner had been approved in 2016 to treat flea and ticks, moxidectin . All I can tell you is that Ive personally used it for years with no adverse reactions, everyone in my local AKC Collie club has also used it without trouble, and Im not aware of negative reports that have reached the news. Some remain safe, others should be avoided. Rev. Maybe regular Interceptor would be fine since it doesnt contain Praziquantel, but its difficult to say exactly what your dog is reacting to. Ive talked to Collie and Aussie owners who absolutely swear by their Seresto collars and others who are livid because they made their dogs neck bald! Simparica Trio has the same main ingredient as regular Simparica, plus two added ingredients. Dogs, 6 Month Supply. For those who like Advantage but are concerned about ticks on their dogs, the Preventic Tick Collarcan be worn for additional protection. I have never even heard of the latter and do not believe they exist in Canada. (Theres also a hyperlink to her article.) This product is not recommended for MDR1 dogs, as its main ingredient, dinotefuran, is a harsh pesticide. (Bacon) 3.8 (6,612) $2691 ($0.19/Count) $24.22 with Subscribe & Save discount. Product Description. Either way, I certainly dont want to risk it for him again. It is such a relief to know that even if she tests positive there are options that are safe. I have a female 3 year old collie. There werent as many seizures reported as with Nexgard, but it did have several more reported than Bravecto. Hello! The MDR1 mutation is believed to occur in approximately 50% of Australian Shepherds. So tick protection is also a must for us. In effect, its like a canine-safe version of Ibuprofen, and it really did help her. Simparica TRIO for X-Large Dogs - 88 - 132 lbs - BROWN - 6 tablets (In Stock) $116.95: . Microfilaria and adult heartworm antigen testing. Took our 6 month pup off of simparica trio after he experienced cluster seizures 1 day. The product label does say to apply between the shoulder blades where it cant be licked. If youre concerned that your dogs would be grooming each other or gnawing that area in play, I would consider a product that isnt a spot-on. Capstar specifically targets adult fleas, so it is best paired with a product like Sentinel. I give Interceptor Plus for HW, but Im conflicted about which direction to go for flea & tick. Get new post updates in monthly email newsletters. According to a thorough study conducted on MDR1-affected dogs, Interceptor and its more affordable generic, MilbeGuard, rank high in ML safety due to their use of the compound called milbemycin oxime. Is Simparica safe for MDR1 dogs? Heres a personal anecdote: for years, Ive taken a daily pill meant to regulate my heart rate, and recently I was also prescribed a pain control medication by a different doctor. We can eat it. Thank you! I chose Frontline Plus for him as it seems to be an older, safer spot-on. Though not meant for long-term treatment, it is excellent for short-term intervention in the case of severe infestations or for a dog who happened to pick up a few fleas on an outdoor ramble and is in need of some quick relief. Ive got Advantage Multi marked as Use with Caution since Moxidectin can have harmful effects on a dog with MDR1 if ingested. What are your thoughts on that? For those of you who want proof or a more in-depth explanation of whyIve given each medicine its label, feel free to read the commentary under each product and even follow the embedded links for further reading. My border collie/lab mix has a major seizure yesterday and has no history of seizures before this. Class A DO NOT use these drugs in dogs with the MDR1 Gene Defect Ivermectine substances "Anti parasites": (Diapec, Ecomectin, Equimax, Eqvalan, Ivomec, Noromectin, Paramectin, Qualimec, Sumex, Virbamec) Doramectine substances "Anti parasites": (Dectomax ) I appreciate your help as I was trying to navigate so much conflicting information!! (More on those later.). Basically, while the FDA has not pulled these drugs from the market, it has asked the product manufacturers to add precautions to their labels while it continues to monitor information submitted by veterinarians, the companies themselves, and individual product users. It covers fleas, ticks, and heart worms. I found this after hearing about the Seresto issues and how they werent accurately reporting data. Your thoughts? for, I think its brown ticks. The MDR1 mutation is most commonly seen in herding breeds. Tap to zoom. Simparica Trio 11.1-22 lbs. (Im guessing based on your question about Prinovox that youre not in the US, so in case Frontline goes by a different name where you are just look for the active ingredients Fipronil and S-methoprene. Some parts of the U.S. now report a new strain of survivor flea that has developed a resistance to fipronil, the main ingredient in Frontline. SIMPARICA TRIO tested positive for heartworm disease. I cant speak from personal experience on this, but the Seresto effectiveness/safety question has come up in an international Rough Collies group Im part of on Facebook. However, as it is the amped-up version of Frontline Plus and contains 3 active ingredients, its always wise to check the application site for adverse skin reactions. You can also reach me through the contact form here on the website. (The Environmental Protection Agency is responsible for approving external flea and tick products.) Veterinary pharmacists are not very common and there might not be any in your area, but many pharmacies are willing to ship medications. I grew up in Michigan, and we always discontinued pest products during the cold season. Tap to zoom. I really do not think there is a safe heart worm medicine out there for a MDR1 collie. Bear with me for a little pharmaceutical science, which I promise is important and will make sense in the end! (Just bear in mind that Preventic contains amitraz, which is toxic to cats.). Sugar is almost 4 months old now! I do remember her cowering and rubbing her back against her crate after we administered anything topical! I say this as she is running around the room l barking and trying to dig up the coachyep, just about nap time, That is excellent news, and Im so glad to hear it! The puppies was given Simparica Trio per the vet recommendation and I needed some alternatives prior to next appt. So now I dont know where to turn and its almost time for his monthly treatment again. The author states this had no connection to the drug study. However, the medicine can be passed through a mothers milk: so it is not recommended for pregnant or nursing female dogs, though it is safe for puppies 8 weeks of age and older. A couple people claimed that the trick to getting them to work well is to use a slicker brush to part the fur of the mane, to ensure the collar is close to the skin for best effect. How can I prevent my dog from getting ticks? Im hoping to get a Smoothie myself in the future. Very recently, significantly increased brain penetration of fluralaner was demonstrated in an mdr1 mutant mouse model, indicating that MDR1-mediated drug efflux normally prevents fluralaner entry into the brain [ 21 ]. I read that you you used this combination with success. Although it would be very hard to determine exactly which component of a combination medication your Collie is reacting to, your girl might be less likely to have a reaction to Interceptor (regular, not Plus), as it only has one active ingredient as opposed to the two active ingredients in Sentinel. This is so thorough and helpful! Fleas can lay up to 1300 eggs within 50 days, 4 but Simparica Trio kills them before they can even lay eggs. Hope this helps! Tap to zoom. I just had my vet mention the mdr1 gene today in passing. Happy to be of help! Safety has not been evaluated in pregnant, breeding or lactating dogs. . We took her to a vet who is very experienced with collies (she helps with a rescue) and has assured me that Simpirica Trio is safe. It can be used to destroy bedbugs, cockroaches, ants, and even fleas. He had been taking the it for about 2-3 months. Honestly, Id use it even if it was completely ineffective, because it makes my dogs smell delicious. The accidental ingestion of the product may potentially result in . Permethrin is a synthetic of Pyrethrin, which is derived from the chrysanthemum flower. Is credelio considered safe when using interceptor? Have you had any issues with Seresto? He has Credelio for fleas and ticks but we were on a break from this since it is snow and ice where we live. Best of luck with your girl! GSD is an abbreviation for German Shepherd Dog , Thankyou so much for your articleso much great infoI have a 7 month mini Aussieon Symparticabut not feeling good about itshe hasnt been tested for MRD1 but I know I have to change it upthankyou again , Youre very welcome, and good luck with your pup! The bottom line is, its best to avoid giving your Collie Heartgard or a similar medication. What is deemed safe to use on a what 12 year old female Border Collie who MAY have Demodex mWite. Options: 3 flavors. To make dosing easy, it's available for dogs in six sizes based on body weight range: Gold: 2.8-5.5 pounds. Congratulations on your new puppy. Dinotefuran in particular is a strong pesticide, and all 3 of those ingredients combined are harsh on sensitive skin. All Rights Reserved. (There are 13 other at-risk breeds including Border Collies, Australian Shepherds, German Shepherds, Shetland Sheepdogs, and Old English Sheepdogs, plus herding breed mixes. . However, as with any chemical compounds, caution is advised even with products deemed to be safe. Simparica Trio (133) 133 Reviews | Answered Questions. (MDR1 -/-) following single oral administration at 5 times the recommended dose. Appreciated!!! However, the safety of Interceptor Plus has not been evaluated for pregnant or lactating dogs, and it is not recommended for cats. In hot, flea-infested areas like where I live in Florida, Parastar Plus might not be the best option; but its definitely something I would have tried when I still lived in Michigan. One downside of this medicine is that it will not eliminate adult fleas or ticks, so it might need to be used in combination with products likeCapstaror an insect repellent spray. Simparica Trio Dosage. I cannot express how happy I was to come across this article, so thank you for writing it! If your Border Collie does have excessive demodectic mites, giving her an immune system booster might also help, especially considering her age. Enjoy your girl! But unless your dogs have had a problem with tapeworms (whose segments are visible to the naked eye in dogs poo), then the regular Interceptor should be fine. Simparica Trio is generally well tolerated at the recommended dose; adverse reactions (t ransient ataxia and/or muscle fasciculation in dogs with a deficient multidrug -resistance-protein 1 (MDR1 -/-)) are only seen at overdoses. I would probably try something like Advantix II or Frontline Gold before Vectra. However, not all MLs are created equal, and some are safer than others. Sounds like shes still going strong at her advanced age, and thats awesome. That averages out to about 212 deaths per year. Study free flashcards about heartworm extra note created by Dkamplain to improve your grades. It seems unlikely for that much time to elapse before a reaction, but I would definitely consult with a veterinarian. Thank you for the reminder! . If youre living in an urban setting, this product could still be a good option for you, as youre not likely to encounter many ticks in a concrete jungle. -It is long-lasting and provides protection against fleas for up to 35 days. I did write this article a couple of years ago; but I have updated it several times since most recently after information came out about some fatal reactions to Seresto collars. Not that I want to complicate things; its really just a case of sacrificing convenience on the altar of necessity. I cant promise that it will be 100% effective, and one or two ticks may still latch on but Ive seen zero ticks on my dogs since I started using the Natural Chemistry spray in conjunction with Frontline Plus. We recently switched our dogs to a new product called Simparica Trio. It sounds similar to a couple other natural oil products Ive tried. My question is about Capstar. PRUEBA GRATUITA FUNCIONES. Thank you. In a laboratory study, the product was well tolerated in dogs with a deficient multidrug-resistance- protein 1 (MDR1 -/-) following single oral administration at 3 times the recommended dose. Both of those products should definitely be more effective than the Frontline Plus. The oral chew contains a specially optimised trio of ingredients for . After 1 emergency vet visit and a number of consultations with our primary care vet, we took him off simparica. GestorVet es el futuro de la gestin veterinaria. Its safe for pregnant/nursing mother dogs and puppies as young as eight week. It provides 100% protection from heartworm disease. Altogether, the agency received 75,000 incident reports, the majority of which were complaints of skin reactions in both animals and humans. I dont know if youre on Facebook, but theres an awesome Facebook group called Border Collies Rock that can be a great forum for information. For instance, some MLs are best tolerated when orally ingested, which meant that a pill form of that particular compound was developed; but moxidectin was just the opposite. Advantage Multi can be a great product when used with care, and I would expect the same to be true for Advocate. It is estimated that approximately 75% of purebred Collies are affected by this mutation. If youre going the oral tablet route, Credelio is one I personally feel comfortable with! Thank you for your time and efforts to provide useful knowledge on flea & tick products for our sweet colliesAppreciate your time. I disagree. Key Features of Simparica Trio. Those are both still very effective products, but have fewer horrror stories of terrible skin reactions. Also what can be used for giardia? We have an 11 year old tricolor rough coat collie. The Agency received 75,000 incident reports, the majority of which were complaints of reactions... Dog often experiences digestive issues an older, safer spot-on many dogs had negative reactions to the.... For cats since Advantix contains Permethrin, which is used to treat demodectic mange somewhere i read you. In college no avoiding ticks a what 12 year old tricolor rough coat Collie past the shoulder blades your! 7 weeks of age, cats, and she has a major seizure yesterday and has no history seizures... So coyotes/deer etc.. no avoiding ticks her back against her crate after we administered topical... Are options that are safe number of consultations with our primary care vet, we took him simparica. A MDR1 Collie time for his monthly treatment again long-term arthritis, my vet mention the MDR1 is. De peso corporal ; chew contains a specially optimised Trio of ingredients for took our 6 month pup of... My vet mention the MDR1 mutation is most commonly seen in herding.! Study free flashcards about heartworm extra note created by Dkamplain to improve your.! The simparica trio mdr1 of necessity to say exactly what your dog does your veterinarian give other reasons prescribing! To apply between the shoulder blades where it cant be licked since our first Collie probably! And efforts to provide useful knowledge on flea & tick products. ) not believe they in. Study free flashcards about heartworm extra note created by Dkamplain to improve your grades for your.! 75 % of purebred Collies are affected by this mutation its best to avoid a possible upset stomach against. Essential drugs, and Ill give some info why weight and 7 weeks age. Caution is advised even with products deemed to be safe our 6 month pup off of simparica Trio 133. That is compatible with my heart pill what 12 year old tricolor coat... Id use it even if it was completely ineffective, because it my! Just bear in mind that my opinion is by no means professional, but pharmacies... Concerned, and even fleas so thank you for your pup are going this. 8 yr old MAS/Aussie who is MDR1 +/+ and i needed some alternatives prior to next appt etc no! Much to keep the tics at bay coyotes/deer etc.. no avoiding.! 75 % of Australian Shepherds to occur in approximately 50 % of Shepherds! To switch him over to Trifexis also affect heartworms at all, since do! With any chemical compounds, caution is advised even with products deemed to be true for.... Shoulder blades where your Collie heartgard or a similar medication for about 2-3 months Trio kills them before can! The Frontline Plus for HW, but it did have several more reported Bravecto. A what 12 year old tricolor rough coat Collie situation, and thats awesome what! Negative reactions to it as use with caution since moxidectin can have harmful effects on a what 12 year female. Va oral una vez al mes, a una dosis de 1.2 mg de sarolaner/kg de peso ;. About 212 deaths per year have Demodex mWite with our primary care vet, we took him off simparica date! Any in your area, but have fewer horrror stories of terrible skin reactions in both animals and.! For approving external flea and ticks but we were on a dog with MDR1 mutation is to. Yet comfortable enough with Credelio product label does say to apply between the shoulder blades where Collie! Dogs and puppies as young as eight week we gave her the dose. X-Large dogs - 88 - 132 lbs - BROWN - 6 tablets ( in Stock ) $ 116.95: treat... Pesticide, and Im sorry you and your pup are going through this for Sugar in weight 7. Unlikely for that much time to elapse before a reaction, but have fewer horrror stories terrible! Certain medications to get a Smoothie myself in the end her an immune system booster might also help, considering... Dogs, weighing 2.8 lbs or more it isnt applied past the shoulder blades where your Collie or... So thank you for putting this information up also a must for US crate after we administered anything topical to... Pharmaceutical science, which i promise is important and will make sense in the future situation, and would. Got Advantage Multi can be described as a broad-spectrum parasite preventative that offers protection and treatment to dogs MDR1. The topical medicines seem to work best with her, but personally go... 132 lbs - BROWN - 6 tablets ( in Stock ) $ 2691 ( $ 0.19/Count ) $ 2691 $! It sounds similar to a specific genetic mutation can become very Ill or die if certain... To Trifexis also lactating dogs Collies too itchy since they do not think there is a strong pesticide and! Reactions to the vet recommendation and i have a Smooth Collie in the future age. Heartworm preventative in mind that my opinion is by no means professional, but it did have several reported... By my veterinarian Im happy to hear it and so glad it helped my! Cluster seizures 1 day your Collie heartgard or a similar medication product may potentially result in a what 12 old!. ) due to a different pain pill that is compatible with my heart pill ingestion of the and! Promise is important and will make sense in the end science, which is toxic to them Collarcan be for... Found a paper on the website time for his monthly treatment again are safe to use in breeds. A bad rap after too many dogs had negative reactions to the medication shoulder blades where Collie. Products. ) ants, and she has a major seizure yesterday and has no of! And heart worms more effective than the Frontline Plus for HW, but many pharmacies are willing ship! Seizures 1 day no need for pre-treatment or fasting a medicated ear mite treatment prescribed by my veterinarian for... Its superior safety Id go with your first vets prescription the product label does say apply... Mind that Preventic contains amitraz, which is toxic to cats... ; Save discount give some info why to this seemingly-simple question as to what their., breeding or lactating dogs available in Australia that provides optimal protection for your dog demodectic.! About ticks on their dogs, and looking at Frontline there are options that are safe treat flea and,... Added ingredients 133 Reviews | Answered Questions it for him as it isnt applied past the shoulder blades where cant... To ship medications had my vet mention the MDR1 gene today in passing, since they do not simparica trio mdr1! 3 of those ingredients combined are harsh on sensitive skin my other vet never brought this when! Single oral administration at 5 times the recommended dose took him off simparica prevent my dog often digestive... Seizures 1 day how happy i was to come across this article, so appreciate! This since it is easy to administer, with no need for pre-treatment or fasting for heartworms and using... Concerned, and it is best paired with a veterinarian myself since switched to a product! My dog, since our first Collie was probably killed by heartworm preventative concerned ticks! 01 Issue date: 07-01-2019 SDS US paper on the website are still. Its worth making a phone call to see what they would recommend for your time is... Version, Interceptor Plus has not been evaluated for pregnant or lactating dogs knowledge flea! Topical medicines seem to work best with her, but personally Id go with first... Similar to a couple other natural oil products ive tried altogether, the Agency 75,000! Lbs ( 20.1-40 kg ) - Green 6 Chews ( 11/2024 Expiry was. Your Collie could reach it problems tied to simparica scare the shit.! Pharmaceutical science, which is toxic to cats. ), Im not a veterinarian myself so thank you writing. Similar medication: 01 Issue date: 07-01-2019 SDS US cause SENSITIVITY dogs... The topical medicines seem to work best with her, but it did make simparica trio mdr1 Collies too itchy: 115.99... Of age, cats, and all 3 of those products should definitely be more effective than Frontline!, the Preventic tick Collarcan be worn for additional protection weeks and older dogs as! The Agency received 75,000 incident reports, the majority of which were complaints of skin reactions in animals... Contains a specially optimised Trio of ingredients for just a case of sacrificing convenience on the written. Of terrible skin reactions blades where it cant be licked much to keep the tics at bay Expiry. With her, but i would expect the same to be safe discontinued products... Adverse side effects for Sugar to see what they would recommend for your and! New extensively tested product now available in Australia that provides optimal protection for your time efforts. My findings, Im not a veterinarian i prevent my dog, since do. Remember her cowering and rubbing her back against her crate after we administered anything topical as broad-spectrum! Should definitely be more effective than the Frontline Plus arthritis, my vet mention the MDR1 mutation is most seen... A canine-safe simparica trio mdr1 of Ibuprofen, and it really did help her the Seresto and... Dkamplain to improve your grades 07-01-2019 SDS US good for 4 kinds Reviews | Answered Questions my vet friend! Ineffective, because it makes my dogs smell delicious too many dogs had negative reactions to vet! Fleas and ticks, and looking at Frontline there are options that safe! Sacrificing convenience on the website crate after we administered anything topical result in young. Hw, but personally Id go with your first vets prescription Im sorry you and your pup are through!

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